Welcome to the website of the Chemometrics & Advanced Separations Team (CAST) of the University of Amsterdam and VU Amsterdam University. The team comprises enthusiastic researchers from both universities who devote a bit of their time to developing guides and tools for use by the community. Here, you will be able to find useful, information, software and tools for use in multi-dimensional chromatography.
PhD candidate Mimi den Uijl has together with her co-workers reviewed recent applications of retention modelling in LC. In the review, den Uijl furthermore identified key application areas where retention modelling received a significant degree of interest.
What are the latest developments around detection techniques for (polymer) LC? Where are the opportunities? Our talented PhD candidate and colleague Wouter Knol answers these and more questions in his open-access review published in Journal of Separation Sciences together with polymer expert Prof. Ron Peters.
A joint study by the University of Waterloo (Prof. Tadeusz Górecki), the Stellenbosch University (Prof. Andre de Villiers) and the University of Amsterdam (Dr. Bob Pirok) was just published in Journal of Chromatography A. In the study, parallel gradients are evaluated as alternative for shifted gradients in comprehensive 2D-LC.
MSc. graduate student Denice van Herwerden wrote a book chapter on contemporary LC techniques for samples related to oil, refining, and wastewater encountered in the oil and petrochemical industries. Covering group-type separations and distribution determinations, Van Herwerden also reviewed promising techniques currently in development.
Bob Pirok and Johan Westerhuis from the University of Amsterdam published an article earlier this month in LC-GC North America. The authors identify key challenges in data analysis in 1D and 2D chromatography. The article is accessible for free.
CAST members Tijmen Bos, Wouter Knol, Leon Niezen and Stef Molenaar compiled an overview of applications and developments of chemometrics applied to one- and two-dimensional chromatography. The review was recently published in Journal of Separation Science.
We maintain a searchable database containing all 2D-LC methods published since the 1978 paper by Erni and Frei. The database, which contains over 550 methods, is part of a collaboration between the University of Amsterdam (Pirok) and Gustavus Adolphus College (Stoll).